Monday 20 May 2019

SABER tech gives DNA and RNA visualization a boost

Researchers have been using "Fluorescence in situ hybridization" (FISH) analysis for decades to literally fish for specific DNA and RNA sequences in intact cells and tissues within their vast seas of nucleic acid molecules. Because of its ability to light specific sequences up under the microscope at the exact locations at which they reside, FISH has come to be a go-to method in the diagnosis of chromosomal abnormalities, investigation of the 3-D organization of genomes in cells' nuclei, analysis of the immediate products of gene expression known as messenger RNAs and more.

* This article was originally published here

Researchers demonstrate double-lock protection mechanism in crucial cellular switches

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have used CRISPR technology to probe the mechanisms that guide the developmental trajectories of stem cells in the brain. The results show that crucial cellular switches are doubly protected against unintended activation.

* This article was originally published here

Researchers discover placental stem cells that can regenerate heart after heart attack

Researchers at the Icahn School of Medicine at Mount Sinai have demonstrated that stem cells derived from the placenta known as Cdx2 cells can regenerate healthy heart cells after heart attacks in animal models. The findings, published in the May 20 issue of Proceedings of the National Academy of Sciences (PNAS), may represent a novel treatment for regenerating the heart and other organs.

* This article was originally published here

Just like toothpaste: Fluoride radically improves the stability of perovskite solar cells

Solar cells made of perovskite hold much promise for the future of solar energy. The material is cheap, easy to produce and almost as efficient as silicon, the material traditionally used in solar cells. However, perovskite degrades quickly, severely limiting its efficiency and stability over time. Researchers from Eindhoven University of Technology, energy research institute DIFFER, Peking University and University of Twente have discovered that adding a small amount of fluoride to the perovskite leaves a protective layer, increasing stability of the materials and the solar cells significantly. The solar cells retain 90 percent of their efficiency after 1000 hours operation at various extreme testing conditions. The findings are published today in the leading scientific journal Nature Energy.

* This article was originally published here

Researchers imagine a cheaper, fairer marketplace for digital goods

E-commerce is sizzling. Last year, consumers spent more than $517 billion online with US merchants, up 15 percent from the year before, according to Internet Retailer.

* This article was originally published here